The recipients of the TTS Young Investigator Scientific Awards submitted abstracts to the 2018 Congress and received the highest scores from an international panel of reviewers.

• Rebeca Arroyo Hornero, United Kingdom
  Co-Stimulatory Modulation of Human Regulatory T cells for Enhanced Immunotherapy

• Yarl Balachandran, United States
  Delineation of the Viral and Host Cell Genomic Alterations in EBV-positive PTLD

• Florencia Bonisconti, Argentina
  Clinical Utility of a Modified qRT-PCR for Trypa- nosoma Cruzi Detection in Transplant Patients

• Xiaoyong Chen, People's Republic of China
  Characterization of a CD23+CD43+ Regulatory B Cell Subset in Human that Induced by Mesenchymal Stem Cells

• Aravind Cherukuri, United States
  Prospective Multicenter Validation of Human Transitional B cell Cytokines as a Predictive Biomarker in Renal Transplantation

• Fang Kuan Chiou, Singapore
  Poorer Long-Term Survival Associated with Monomorphic Post-Transplant Lymphoproliferative Disorder After Solid Organ Transplantation in Children

• Dominik Chittka United States
  DSA plus TCMR Leads to Poor Outcomes in Renal Allograft Recipients and this is Markedly Exacerbated by Non-Adherence

• Helong Dai, People's Republic of China
  Distal Abdominal Aorta Could Serve as an Out-flow Tract for en Bloc Kidney Transplantation from Infant Donors with Extremely Low Body Weight

• Nicole De La Mata, Australia
  Stroke Mortality in Kidney Transplant Recipients: A Retrospective Population-Based Cohort Study using Data Linkage

• Reinier de Vries, United States
  Extending the Human Liver Preservation Time for Transplantation by Supercooling

• Su Kah Goh, Australia
  Donor-Specific Cell-Free DNA as an Emerging Biomarker of Organ Rejection after Liver Transplantation

• Christian Heim, Germany
  Blockade of Tyrosine Kinases as Preventive Strategy Against Cardiac Allograft Vasculopathy in a Murine Aortic Transplant Model

• Charlotte Lee, United Kingdom
  The Anti-Inflammatory Effect of Alpha-1 Antitrypsin in Hepatocyte Transplantation

• Xiaoqian Ma, People's Republic of China
  Cord Blood Derived Regulatory Macrophages (Mreg) – An Alternative Source for Mreg-based Cell Therapy in Transplantation

• Berenice Mbiribindi, United States
  NK Cell Recognition of Peptides Encoded by EBV Latent Cycle Proteins

• Hiroyuki Ogasawara, Japan
  A Comparison of the Transplant Efficiency between Intraportal and Intrasplenic Procedures in Hepatocyte Transplantation

• Brenda Rosales, Australia
  Cancer Mortality in Transplant Recipients in Australia and New Zealand: A National Cohort Study from 1980 to 2013

• Akhil Sharma, United States
  Pro-inflammatory B Cells Predict Progressive Minimal Early Renal Allograft Inflammation Which Is Associated With Poor Graft Outcomes

• Nicole Shockcor, United States
  End Stage Renal Disease as a Complication of Face Transplant

• Ashley Suah, United States
  Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells

• Patrick Trotter, United Kingdom
  Transplantation of Kidneys from DCD and DBD Donors who Died after Ligature Asphyxiation: the UK Experience

• Marieke van der Zwan, The Netherlands
  Efficacy of Rabbit Anti-Thymocyte Globulin Therapy for Severe Acute Rejection in Kidney Transplant Patients using Calcineurin Inhibitor and Mycophenolate Mofetil based ImmunosuppressiveTherapy

• Karen Waller, Australia
  Incidence, Prevalence and Residual Infection Risk of HIV in Increased Risk Groups Presenting as Potential Organ Donors in Australia; A Systematic Review and Meta-Analysis

• Casey Ward, United States
  Reversal of Diabetes and Preservation of Pancreatic Islet Grafts in the Extrahepatic Space with Novel Parathyroid Gland Co-Transplantation

• Cheng Yang, People's Republic of China
  Prediction of Renal Allograft Chronic Rejection using a Model Based on Contrast Enhanced Ultrasonography

• Yuanfei Zhao, Australia
  In-vivo Costimulation-Blockade induced Foxp3 Tregs from DEREG Mice with Neonatal Islet Cell Cluster Tolerant Xenografts Exist Memory Tregs Phenotype

• PENELOPE ALLEN, Australia
  The impact of recurrent glomerulonephritis after kidney transplantation in the era of contemporary maintenance immunosuppression

• VAISHNAVI CALISA, Australia
  The relative costs and health benefits of an age-matched deceased donor allocation algorithm compared to current practice

• ARAVIND CHERUKURI, United States
  Early de novo DSA with T Cell Mediated Rejection (TCMR) is Associated with Allograft Dysfunction with Chronic Injury

• JASON DAVIS, Unites States
  Changes in liver allograft steatosis and its impact on early graft function and long term survival

• DENIS EFIMOV, Belarus
  DAMP-associated preservation injury and complications after liver transplantation: proof of concept

• SHAIMAA ELKHOLY, Egypt
  Predictors of Mortality In Living Donor Liver Transplantation

• JIANING FU, United States
  Generation of naïve donor-derived lymphocytes from graft-resident lymphoid progenitors after human intestinal transplantation

• BARBARA KERN, Australia,
  Nonalcoholic Steatohepatitis as Indication for Liver Transplantation in Europe. Clinical Analysis of over 37.000 Patients

• QIANG LIU, United States
  Triglyceride exportation in the preservation of discarded steatotic human livers using 24 hours ex-vivo normothermic machine perfusion

• DAVID NASRALLA, Unites Kingdom
  A Multicentre Randomised Controlled Trial to Compare the Efficacy of Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation: Early Outcomes

• KEVIN TAK-PAN NG, Hong Kong
  Up-regulation of GSTA2 at early-phase after liver transplantation increases the risk of late-phase hepatocellular carcinoma recurrence

• THOMAS SCHACHTNER, Germany
  Kinetics of CMV-specific T-cells From Pre-to-Posttransplantation Predict Outcomes in CMV-seronegative Kidney Transplant Recipients

• OSCAR SERRANO, United States
  Defining the tipping point in surgical performance in laparoscopic donor nephrectomy during abdominal transplant surgery fellowship: a learning curve analysis.

• RASHMI SHINGDE, Australia
  Trojan Kidneys: Unexpected Donor-Derived Viral Transmission in Kidney Transplant Recipients – a Systematic Review

• UMANG THAKKAR, India
  Stem cell therapy as an emerging modality for post-traumatic paraplegia and for renal parenchymal diseases

• MIRJAM TIELEN, Netherlands
  Importance of Early Medication Adherence for Long-Term Graft Survival: A Prospective, Single-Centre Cohort Study

• THOMAS VANHOVE, Belgium
  Tubulointerstitial expression of connective tissue growth factor in renal allograft protocol biopsies at 3 months predicts interstitial fibrosis at 5 years

• GEORGIOS VRAKAS, United Kingdom
  De Novo Donor-Specific HLA Antibodies after Combined Intestinal and Vascularized Composite Allotransplantation

• JOHANNES WEDEL, United States
  DEPTOR modulates alloimmunity by increasing regulatory T cell function and stabilizing Foxp3 expression

• CHENG YANG, China
  Cyclic Helix B Peptide Inhibits Ischemia Reperfusion-induced Renal Fibrosis via the PI3K/Akt/FoxO3a Pathway

• WAI HO OSCAR YEUNG, Hong Kong
  Dysregulation of transforming growth factor beta receptor III induces tumor promoting macrophages via complement C3a in Hepatocellular Carcinoma recurrence after liver transplantation

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc.

• Deyaa El Deen Morsy
  Lymphocytes Can Play The Trojan-Horse Role in Polyoma BKV Infection

• Liang Wei
  The MicroRNA miR-182 Alters CD4+ T Cell Responses Post-Transplant

• Sharmila Ramessur
  The Role of Spleen Tyrosine Kinase in Acute Renal Allograft Rejection in the Rat

• Carolina Moore
  Clonal Composition and Specificity of Graft Infiltrating B Cells in Human Cardiac Allograft Vasculopathy

• Fadi Issa
  Evaluation and Optimisation of Non-Autologous Human Regulatory T Cell Therapy for Transplantation

• Seiichi Shimizu
  Association ofFc-gamma Receptor Gene Polymorphisms With Susceptibility to Bloodstream Infections After Liver Transplantation

• Masaaki Zaitsu
  Anti-CD28 Antagonism Using a Monovalent Fab Antibody for the Prolongation of Human Skin Allograft Survival

• Toshihito Hirai
  A Novel Approach Inducing Transplant Tolerance By Activated Invariant Natural Killer T Cells With Co Stimulatory Blockade

• Katrien De Vusser
  Intrarenal Telomere Length and Intrarenal Arteriosclerosis in Pretransplant Kidney Biopsies

• Silke Roedder
  A 17 Gene Blood Assay (kSORT) for Diagnosis and Prediction of Acute Renal Transplant Rejection: Results of the Multicenter AART Study

• Karolina M. Burghardt
  Proposed Listing Indications for Pediatric Intestinal Transplant in the New Era of Specialized Care for Intestinal Failure

• Goutham Kumar
  Predictors For Better Graft Survival After Intestinal and Multivisceral Transplantation

• Yuk Man (Kevin) Lei
  The Microbiota Promotes Skin Allograft Rejection

• Yanbao Xiong
  Treg Require Transcription Factor T-bet to Traffic to Draining Lymph Nodes and Prolong Islet Allograft Survival

• S. Keshwani
  Pre-Transplant T-Cell Subtype Assessment as a Predictive Tool for CMV Viremia After Transplant

• Nissreen Elfadawy
  The Clinical Relevance ofHLA Cw, DQ and DP Mismatches Among The Zero HLA A, B and DR Mismatched Deceased Donor (DD) Kidney Transplant Population

• Esme Dijke
  Pediatric Thymic Tissue as a Novel Source for the Expansion of Stable Regulatory T Cells for Cellular Therapy

• Aunemarie Weissenbacher
  VCA at Innsbruck Medical University - An Update 14 Years After the First Hand Transplantation

• Angelo Alberto Leto Barone
  Either Abatacept or Belatacept in Combination With Donor Bone Marrow Infusion Induces Immune Tolerance Across a Full MHC Barrier in a Translational Large Animal Vascularized Composite Allotransplantation Model

• Jorge Roque Espinosa
  CD57+CD4 T Cells and Belatacept Resistant Rejection

• Makoto Tonsho
  Successful Tolerance Induction of Lung Allografts in Non-Human Primates

• Shruti D. Dave
  Mesenchymal Stem Cells Induced In Vitro Generation of Antigen Specific Regulatory T-Cells Containing CD4+CD8+ Population: A Cell-Based Therapy To Promote Transplantation Tolerance

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc.

Esmé Dijke, Canada Expansion of Highly Suppressive FOXP3+ Regulatory T Cells from Pediatric Thymic Tissue

Vivek Kute, India Novel Strategy for Tolerance Induction in Living Donor Renal Transplantation

Gisele Meinerz, Brazil Increasing Incidence of Tuberculosis after Renal Transplantation in a Brazilian Center

Miwa Morita, USA Liver Stromal Cells Contribute to Liver Transplant Tolerance: Involved Cellular and Molecular Mechanisms

Nicolas Poirier, France Preclinical Evaluation of FR104, An Antagonist Anti-CD28 Monovalent Fab’antibody, in DTH and Kidney Transplant Primates Models

Thomas Rogerson, Australia Tests for Latent Tuberculosis in Potential Transplant Recipients: A Systematic Review

Moritz Schmelzle, USA Increased Plasma Levels of CD133+ Microparticles Bearing Ectonucleotidases Are Noted in Acute Liver Failure in Patients and in Experimental Mouse Models

Tina Schmidt, Germany Comparative Analysis of Assays for Detection of Cellular Immunity Towards CMV and M. Tuberculosis in Samples from Deceased Donors

Adnan Sharif, United Kingdom One-Year Biopsy Data of Antibody-Incompatible Kidney Transplantation and Correlation with Medium-to-Long Term Risk of Allograft Loss – a Prospective Analysis

Simo Syrjälä, Finland Ang1 Reduces Ischemia-Reperfusion Injury–Induced Microvascular Dysfunction and Chronic Rejection in Rat Cardiac Allografts

Supported through an unrestricted educational grand from: 

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc.

Cheguevara Afaneh, USA Differential regulation of positive or negative costimulatory molecules during acute rejection of human renal allografts

Russell Hodgson, Australia Prolonged xenograft survival induced by ICOS-IG Is associated with increased Foxp3+ cells

Faisal Khan, Canada Genomic instability after allogeneic hematopoietic cell transplantation is frequent in oral mucosa, particularly in patients with a history of chronic graft-vs-host disease, and rare in nasal mucosa

Li Li, USA A highly specific novel 3 gene-set can non-invasively predict operational renal allograft tolerance

Luiz Lisboa, Canada In vivo viral microRNA profiling in a large cohort of transplant patients with CMV disease

Kate Markey, Australia GVHD-associated immune suppression is the result of an intrinsic defect in MHC class II antigen presentation within donor DC

Susumu Shibasaki, Japan A single infusion of the ex-vivo generated immunoregulatory dendritic cells under a novel agent, NK026680 markedly prolongs cardiac allograft survival

Kazuaki Tokodai, Japan Interruption of a cross-talk between the complement and coagulation cascades improves early outcomes after intraportal islet transplantation

Hanna Trydzenskaya, Germany New protocol of BKV-specific T cell analysis allows for improved assessment of phenotypic and functional characteristics of BKV-specific immunity

Laura Wozniak, USA Validation of a transcriptional profile of tolerance in pediatric liver transplant recipients

Supported through an unrestricted educational grand from: 

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. since 1994. The recipients in 2006 during the 1^st World Transplant Congress:

Supported through an unrestricted educational grand from: 

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc.

Supported through an unrestricted educational grand from: